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CBAA1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BPX6
Peptide ID 38082
Additional Information
Gene ID 10367
Other Names Calcium uptake protein 1, mitochondrial, Atopy-related autoantigen CALC, ara CALC, Calcium-binding atopy-related autoantigen 1, Hom s 4, MICU1, CALC, CBARA1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MICU1
Synonyms CALC, CBARA1
Function Key regulator of mitochondrial calcium uniporter (MCU) required to increase calcium uptake by MCU when cytoplasmic calcium is high. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, respectively. MICU1 acts as a stimulator of MCU that senses calcium level via its EF-hand domains: enhances MCU opening at high Ca(2+) concentration, allowing a rapid response of mitochondria to Ca(2+) signals generated in the cytoplasm. Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake. Induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG.
Cellular Location Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space Note=Localizes at the outer surface of the mitochondrion inner membrane
Tissue Location Expressed in epithelial cell lines. Strongly expressed in epidermal keratinocytes and dermal endothelial cells
Research Areas
Citations (0)

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Bordicchia, M., et al. Metab. Clin. Exp. (2009) In press :Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)Natter, S., et al. FASEB J. 12(14):1559-1569(1998)

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$ 80.00
Cat# BP9682a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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