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PSMG2 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q969U7
Peptide ID 90713171
Additional Information
Gene ID 56984
Other Names Proteasome assembly chaperone 2, PAC-2, Hepatocellular carcinoma-susceptibility protein 3, Tumor necrosis factor superfamily member 5-induced protein 1, PSMG2 {ECO:0000312|EMBL:AAH133561}
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PSMG2 {ECO:0000312|EMBL:AAH13356.1}
Function Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q9EST4}.
Tissue Location Widely expressed with highest levels in lung, brain and colon. Moderately expressed in muscle, stomach, spleen and heart. Weakly expressed in small intestine, pancreas and liver. Highly expressed in hepatocellular carcinomas with low levels in surrounding liver tissue.
Research Areas
Citations (0)

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Background

Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization.

References

Cooper, J.D., et al. Nat. Genet. 40(12):1399-1401(2008)Barrett, J.C., et al. Nat. Genet. 40(8):955-962(2008)Miyagawa, H., et al. Rheumatology (Oxford) 47(2):158-164(2008)Parkes, M., et al. Nat. Genet. 39(7):830-832(2007)

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$ 80.00
Cat# BP9698b
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