|Other Names||Leucine-rich repeat transmembrane neuronal protein 1, LRRTM1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein|
|Tissue Location||Predominantly expressed in forebrain regions including thalamus and cerebral cortex|
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LRRTM1 may play a role during the development of specific forebrain structures by influencing neuronal differentiation and connectivity, with a possible role in intracellular trafficking within axons.
Francks, C. Laterality 14(1):11-16(2009)Crow, T.J., et al. Laterality 14(1):3-10(2009)McManus, C., et al. Laterality 14(1):1-2(2009)
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