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DBN1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q16643
Peptide ID 90921078
Additional Information
Gene ID 1627
Other Names Drebrin, Developmentally-regulated brain protein, DBN1, D0S117E
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DBN1
Synonyms D0S117E
Function Drebrins might play some role in cell migration, extension of neuronal processes and plasticity of dendrites. Required for actin polymerization at immunological synapses (IS) and for CXCR4 recruitment to IS.
Cellular Location Cytoplasm. Cytoplasm, cell cortex. Cell junction. Note=In the absence of antigen, evenly distributed throughout subcortical regions of the T-cell membrane and cytoplasm. In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation clusters (SMAC)
Tissue Location Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas. Expressed in peripheral blood lymphocytes, including T-cells (at protein level).
Research Areas
Citations (0)

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DBN1 is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease.


Geraldo, S., et al. Nat. Cell Biol. 10(10):1181-1189(2008)Julien, C., et al. J. Neurosci. Res. 86(10):2292-2302(2008)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 80.00
Cat# BP9736a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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