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B3GALTL Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q6Y288
Peptide ID 90826056
Additional Information
Gene ID 145173
Other Names Beta-1, 3-glucosyltransferase, Beta3Glc-T, 241-, Beta-3-glycosyltransferase-like, B3GALTL, B3GTL
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name B3GLCT (HGNC:20207)
Synonyms B3GALTL, B3GTL
Function O-glucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. Specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.
Cellular Location Endoplasmic reticulum membrane {ECO:0000255|PROSITE-ProRule:PRU10138, ECO:0000269|PubMed:16899492}; Single-pass type II membrane protein
Tissue Location Widely expressed, with highest levels in testis and uterus.
Research Areas
Citations (0)

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Background

The protein encoded by this gene is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS).

References

Dassie-Ajdid, J., et al. Clin. Genet. 76(5):490-492(2009)Reis, L.M., et al. Am. J. Med. Genet. A 146A (20), 2603-2610 (2008) Hess, D., et al. J. Biol. Chem. 283(12):7354-7360(2008)Kozma, K., et al. J. Biol. Chem. 281(48):36742-36751(2006)Sato, T., et al. Glycobiology 16(12):1194-1206(2006)

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$ 80.00
Cat# BP9779b
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