PATL1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q86TB9 |
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Gene ID | 219988 |
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Other Names | Protein PAT1 homolog 1, PAT1-like protein 1, Protein PAT1 homolog b, Pat1b, hPat1b, PATL1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PATL1 |
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Function | RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs (PubMed:17936923, PubMed:20543818, PubMed:20584987, PubMed:20852261). Acts as a scaffold protein that connects deadenylation and decapping machinery (PubMed:17936923, PubMed:20543818, PubMed:20584987, PubMed:20852261). Required for cytoplasmic mRNA processing body (P- body) assembly (PubMed:17936923, PubMed:20543818, PubMed:20584987, PubMed:20852261). |
Cellular Location | Cytoplasm, P-body. Nucleus. Nucleus, PML body. Nucleus speckle. Note=Predominantly cytoplasmic (PubMed:22090346). Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner (PubMed:22090346). Enriched in splicing speckles Localization to nuclear foci and speckles requires active transcription. Excluded from the nucleolus (PubMed:22090346) |
Tissue Location | Ubiquitous.. |
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Provided below are standard protocols that you may find useful for product applications.
References
Scheller, N., et al. Biochim. Biophys. Acta 1773(12):1786-1792(2007)Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
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