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HSD17B11 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8NBQ5
Peptide ID 91102031
Additional Information
Gene ID 51170
Other Names Estradiol 17-beta-dehydrogenase 11, 17-beta-hydroxysteroid dehydrogenase 11, 17-beta-HSD 11, 17bHSD11, 17betaHSD11, 17-beta-hydroxysteroid dehydrogenase XI, 17-beta-HSD XI, 17betaHSDXI, Cutaneous T-cell lymphoma-associated antigen HD-CL-03, CTCL-associated antigen HD-CL-03, Dehydrogenase/reductase SDR family member 8, Retinal short-chain dehydrogenase/reductase 2, retSDR2, HSD17B11, DHRS8, PAN1B
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HSD17B11
Synonyms DHRS8, PAN1B, SDR16C2
Function Can convert androstan-3-alpha,17-beta-diol (3-alpha- diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor- associated antigen in cutaneous T-cell lymphoma.
Cellular Location Secreted.
Tissue Location Present at high level in steroidogenic cells such as syncytiotrophoblasts, sebaceous gland, Leydig cells, and granulosa cells of the dominant follicle and corpus luteum. In lung, it is detected in the ciliated epithelium and in acini of adult trachea, in bronchioles, but not in alveoli. In the eye, it is detected in the nonpigmented epithelium of the ciliary body and, at lower level, in the inner nuclear layer of the retina (at protein level). Widely expressed. Highly expressed in retina, pancreas, kidney, liver, lung, adrenal, small intestine, ovary and heart.
Research Areas
Citations (0)

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Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones.


Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) Nakamura, Y., et al. Neoplasma 56(4):317-320(2009)Horiguchi, Y., et al. Arch. Biochem. Biophys. 479(2):121-130(2008)Hartmann, T.B., et al. Br. J. Dermatol. 150(2):252-258(2004)Chai, Z., et al. Endocrinology 144(5):2084-2091(2003)

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$ 80.00
Cat# BP9799a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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