SEC14L1 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q92503 |
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Gene ID | 6397 |
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Other Names | SEC14-like protein 1, SEC14L1, SEC14L |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SEC14L1 |
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Synonyms | SEC14L |
Function | May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of RIGI, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of RIGI with MAVS/IPS1, an important step in signal propagation (PubMed:23843640). May also regulate the SLC18A3 and SLC5A7 cholinergic transporters (PubMed:17092608). |
Cellular Location | Cytoplasm. Golgi apparatus |
Tissue Location | Ubiquitous.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the SEC14 cytosolic factor family. It has similarity to yeast SEC14 and to Japanese flying squid RALBP which suggests a possible role of the gene product in an intracellular transport system.
References
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)Kalikin, L.M., et al. Mamm. Genome 12(12):925-929(2001)Chinen, K., et al. Cytogenet. Cell Genet. 73(3):218-223(1996)
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