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SEC14L1 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q92503
Peptide ID 42944
Additional Information
Gene ID 6397
Other Names SEC14-like protein 1, SEC14L1, SEC14L
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEC14L1
Synonyms SEC14L
Function May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation (PubMed:23843640). May also regulate the SLC18A3 and SLC5A7 cholinergic transporters (PubMed:17092608).
Cellular Location Cytoplasm. Golgi apparatus
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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Background

The protein encoded by this gene belongs to the SEC14 cytosolic factor family. It has similarity to yeast SEC14 and to Japanese flying squid RALBP which suggests a possible role of the gene product in an intracellular transport system.

References

Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)Kalikin, L.M., et al. Mamm. Genome 12(12):925-929(2001)Chinen, K., et al. Cytogenet. Cell Genet. 73(3):218-223(1996)

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$ 80.00
Cat# BP9804c
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