SARDH Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9UL12 |
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Gene ID | 1757 |
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Other Names | Sarcosine dehydrogenase, mitochondrial, SarDH, BPR-2, SARDH, DMGDHL1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SARDH (HGNC:10536) |
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Synonyms | DMGDHL1 |
Function | Catalyzes the last step of the oxidative degradation of choline to glycine. Converts sarcosine into glycine. |
Cellular Location | Mitochondrion matrix {ECO:0000250|UniProtKB:Q64380} |
Tissue Location | Expressed in pancreas, liver and kidney. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, which catalyzes a reaction resulting in the formation of sarcosine.
References
Franke, B., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 85(3):216-226(2009)Gilbert, J.R., et al. Hum. Hered. 50(3):151-157(2000)Eschenbrenner, M., et al. Genomics 59(3):300-308(1999)Bergeron, F., et al. Eur. J. Biochem. 257(3):556-561(1998)
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