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FGF6 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P10767 |
|---|
| Gene ID | 2251 |
|---|---|
| Other Names | Fibroblast growth factor 6, FGF-6, Heparin secretory-transforming protein 2, HST-2, HSTF-2, Heparin-binding growth factor 6, HBGF-6, FGF6, HST2, HSTF2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | FGF6 |
|---|---|
| Synonyms | HST2, HSTF2 |
| Function | Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration. |
| Cellular Location | Secreted, extracellular space. |
| Tissue Location | Leukemia cell lines with platelet/ megakaryocytic differentiation potential |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.
References
Moffa, A.B., et al. J. Cell. Physiol. 210(3):720-731(2007)Zhang, X., et al. J. Biol. Chem. 281(23):15694-15700(2006)Popovici, C., et al. J. Biol. Chem. 279(38):40146-40152(2004)Duplan, S.M., et al. Clin. Cancer Res. 8(1):246-257(2002)
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