|Description||IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on M cells as measured by the dose-dependent stimulation of the proliferation of M CTLL cells. Recombinant rat IL-15 is a 13.5 kDa protein consisting of 115 amino acid residues.|
|BiologicalActivity||The ED50 as determined by the dose-dependant stimulation of the proliferation of murine CTLL-2 cells is < 10 ng/ml, corresponding to a specific activity of > 1 x 105 units/mg.|
|Authenticity||Verified by N-terminal and Mass Spectrometry analyses (when applicable).|
|Endotoxin||Endotoxin level is <0.1 ng/ µg of protein (<1EU/ µg).|
|Protein Content||Verified by UV Spectroscopy and/or SDS-PAGE gel.|
|Precautions||Recombinant Rat IL-15 is for research use only and not for use in diagnostic or therapeutic procedures.|
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