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BDNF, human recombinant protein

Brain Derived Neurotrophic Factor

     
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Product info
Primary Accession P23560
Calculated MW 27.0 kDa
Additional Info
Gene ID 627
Gene Symbol BDNF
Other Names Brain-derived neurotrophic factor, Short name=BDNF, Abrineurin
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC; ≥98%
Recombinant Yes
Results 0.1-1.0 ng/ml.
Target/Specificity BDNF
Application Notes Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Format Lyophilized protein
Storage -20°C; Sterile filtered and lyophilized with no additives
Citations (0)

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Background

Human Brain-Derived Neurotrophic Factor (BDGF) is a potent neurotrophic factor that supports the growth and survivability of nerve and glial cells. The active form of BDNF is a 27.0 kDa dimer, formed by two identical 119 amino acid subunits held together by strong hydrophobic interactions.

References

Jones K.R.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:8060-8064(1990).
Maisonpierre P.C.,et al.Genomics 10:558-568(1991).
Shintani A.,et al.Biochem. Biophys. Res. Commun. 182:325-332(1992).
Liu Q.-R.,et al.Am. J. Med. Genet. B Neuropsychiatr. Genet. 134:93-103(2005).
Pruunsild P.,et al.Genomics 90:397-406(2007).

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$ 190.00
$ 525.00
$ 1,750.00
Cat# PBV10037r
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(40 western blots)
Availability: 5-7days
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