Procalcitonin, human recombinant protein
Procalcitonin, calcitonin, CALCA; CALC1; CGRP; CGRP-I; CGRP1; CT; KC; MGC126648
|Calculated MW||13. 2 kDa|
|Other Names||Procalcitonin, calcitonin, CALCA; CALC1; CGRP; CGRP-I; CGRP1; CT; KC; MGC126648|
|Application Notes||Centrifuge the vial prior to opening. Reconstitute in sterile H₂O to a concentration of 0.1 mg/ml.|
|Storage||-20°C; Lyophilized from a 10 mM sodium phosphate buffer, pH 7.5.|
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Provided below are standard protocols that you may find useful for product applications.
Procalcitonin is a peptide hormone mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, an N terminal residue, calcitonin and katacalcin. Levels of unprocessed Procalcitonin rise significantly after bacterial infection, trauma or shock. Recombinant Human Procalcitonin produced in E.coli is a single, non-glycosylated, polypeptide chain containing 116 amino acids with a molecular weight of 12,796 Daltons.
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Craig R.K.,et al.Biochem. Soc. Symp. 52:91-105(1986).
Riley J.H.,et al.FEBS Lett. 198:71-79(1986).
Minvielle S.,et al.J. Biol. Chem. 266:24627-24631(1991).
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