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SETD3 Blocking peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q86TU7 |
|---|---|
| Gene ID | 84193 |
| Calculated MW | 67257 Da |
| Gene ID | 84193 |
|---|---|
| Application & Usage | The peptide is used for blocking the antibody activity of SETD3. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C |
| Other Names | Histone-lysine N-methyltransferase setd3, 2.1.1.43, SET domain-containing protein 3, SETD3, C14orf154 |
| Target/Specificity | SETD3 |
| Formulation | 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA and 0.02% thimerosal. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | SETD3 Blocking peptide is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SETD3 |
|---|---|
| Function | Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-73' (PubMed:30526847, PubMed:30626964, PubMed:30785395, PubMed:31388018, PubMed:31993215). Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery (PubMed:30626964). Does not have protein-lysine N- methyltransferase activity and probably only catalyzes histidine methylation of actin (PubMed:30626964, PubMed:30785395, PubMed:31388018). |
| Cellular Location | Cytoplasm. Nucleus Note=Localizes mainly in the cytoplasm. |
Research Areas
Citations (0)
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Application Protocols
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