|Calculated MW||64824 Da|
|Application & Usage||The peptide is used for blocking the antibody activity of TCTN3. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.|
|Other Names||Tectonic-3, Tctn3, Tect3|
|Formulation||50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.|
|Reconstitution & Storage||-20 °C|
|Precautions||TCTN3 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. May be involved in apoptosis regulation (By similarity). Necessary for signal transduction through the sonic hedgehog (Shh) signaling pathway.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
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