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IL-32 alpha, human recombinant protein
NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd, IL-32β, IL-32α, IL-32delta, IL-32γ, Interleukin-32, IL-32, Na
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P24001 |
|---|---|
| Calculated MW | 14.9 kDa |
| Gene ID | 9235 |
|---|---|
| Gene Symbol | IL32- α |
| Other Names | NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd, IL-32β, IL-32α, IL-32delta, IL-32γ, Interleukin-32, IL-32, Natural killer cells protein 4, Tumor necrosis factor α-inducing factor, IL-32a, IL32a, IL32, Interleukin-32 α. |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥97% |
| Assay2&Purity2 | HPLC; |
| Recombinant | Yes |
| Results | In progress |
| Target/Specificity | IL-32 alpha |
| Application Notes | It is recommended to reconstitute the lyophilized product with sterile H₂O at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions. |
| Format | Lyophilized protein |
| Storage | -20°C; Lyophilized from 50 mM NaP, pH 7.5. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Human IL-32 α is one of approximately 6 splice variants of a gene cloned from the human lung carcinoma stable transfectant, A549-Rβ. IL-32 α has been shown to induce IL-8, TNF-α, and MIP-2 production from human & mouse macrophage cell lines. It is up-regulated in activated T- & NK-cells, and IFN-g-treated epithelial cells. Human recombinant IL-32 α produced in E. coli is a 131 amino acid non-glycosylated polypeptide with a molecular mass of 14.9 kDa.
References
Dahl C.A.,et al.J. Immunol. 148:597-603(1992).
Kim S.-H.,et al.Immunity 22:131-142(2005).
Mao W.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Oh J.H.,et al.Mamm. Genome 16:942-954(2005).
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