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TTP Blocking Peptide

Product Information
Primary Accession P26651
Gene ID 7538
Calculated MW 34003 Da
Additional Information
Gene ID 7538
Application & Usage The peptide is used for blocking the antibody activity of TPP. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Tristetraprolin, TTP, G0/G1 switch regulatory protein 24, Growth factor-inducible nuclear protein NUP475, Protein TIS11A, TIS11, Zinc finger protein 36 homolog, Zfp-36, ZFP36, G0S24, RNF162A, TIS11A, TTP
Target/Specificity TTP
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsTTP Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZFP36
Synonyms G0S24, RNF162A, TIS11A, TTP
Function mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post- transcriptional regulation of tumor necrosis factor (TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).
Cellular Location Nucleus. Cytoplasm. Note=Localizes to stress granules upon energy starvation. phosphorylation by MAPKAPK2 promotes exclusion from stress granules
Research Areas
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$ 95.00
Cat# PBV10228b
(40 western blots)
Availability: 5-7days
Bulk Size
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