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Wnt-4 Blocking Peptide

     
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Product Information
Primary Accession P56705
Other Accession BAC23080
Gene ID 54361
Calculated MW 39052 Da
Additional Information
Gene ID 54361
Application & Usage The peptide is used for blocking the antibody activity of active Wnt-4. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C
Other Names Protein Wnt-4, WNT4
Target/Specificity Wnt-4
Formulation 50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsWnt-4 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WNT4
Function Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in the embryonic development of the urogenital tract and the lung (PubMed:15317892, PubMed:16959810, PubMed:18179883, PubMed:18182450). Required for normal mesenchyme to epithelium transition during embryonic kidney development. Required for the formation of early epithelial renal vesicles during kidney development (By similarity). Required for normal formation of the Mullerian duct in females, and normal levels of oocytes in the ovaries (PubMed:15317892, PubMed:16959810, PubMed:18182450). Required for normal down-regulation of 3 beta-hydroxysteroid dehydrogenase in the ovary (PubMed:15317892, PubMed:16959810, PubMed:18182450). Required for normal lung development and for normal patterning of trachael cartilage rings (By similarity).
Cellular Location Secreted, extracellular space, extracellular matrix
Research Areas
Citations (0)
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Discontinued
Cat# PBV10240b-50
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