PPARɣ, Human, recombinant protein
Peroxisome proliferator-activated receptor γ, PPAR-γ, PPARG, NR1C3, PPARG1, PPARG2.
|Calculated MW||59.2 kDa|
|Other Names||Peroxisome proliferator-activated receptor γ, PPAR-γ, PPARG, NR1C3, PPARG1, PPARG2.|
|Application Notes||PBS 50% glycerol, 0.01% azide.|
|Storage||-20°C; Sterile-filtered clear solution.|
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Expressed in E. coli fused to an amino terminal hexahistidine tag.The peroxisome proliferator-activated receptor-g (PPAR-g) is a member of the nuclear receptor family of transcription factors, a large and diverse group of proteins that mediate ligand-dependent transcriptional activation and repression. Expression of PPAR-g is an early and pivotal event in the differentiation of adipocytes. PPAR-g influences the storage of fatty acids in the adipose tissue and plays a role in adipocyte differentiation. It also binds to DNA as a heterodimer with retinoid X receptor (RXR), activating expression of target genes after binding ligand.
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