HDAC-11 Blocking Peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96DB2 |
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Gene ID | 79885 |
Calculated MW | 39183 Da |
Gene ID | 79885 |
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Application & Usage | The peptide is used for blocking the antibody activity of HDAC-11. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C. |
Other Names | Histone deacetylase 11, HD11, 3.5.1.98, HDAC11 |
Target/Specificity | HDAC-11 |
Formulation | 50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% sodium azide. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | HDAC-11 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HDAC11 |
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Function | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. |
Cellular Location | Nucleus. |
Tissue Location | Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis |
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