|Calculated MW||56795 Da|
|Application & Usage||The peptide is used for blocking the antibody activity of Endothelial Lipase. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C|
|Other Names||Endothelial lipase, 188.8.131.52, Endothelial cell-derived lipase, EDL, EL, LIPG|
|Formulation||50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.|
|Reconstitution & Storage||-20 °C|
|Precautions||Endothelial Lipase Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has phospholipase and triglyceride lipase activities. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. Binds heparin.|
|Tissue Location||High level of expression in the liver, placenta, lung, thyroid, kidney, testis and in the corpus luteum of the ovary. Expressed also in coronary artery endothelial cells, umbilical vein endothelial cells and in hepatocytes and osteosarcoma cell lines. Not detected in heart, brain and muscle|
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