Register or Login
All
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Math1 Blocking Peptide   

Math1 Blocking Peptide

     
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Primary Accession Q92858
Gene ID 474
Additional Information
Application & Usage The peptide is used for blocking the antibody activity of Math1. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Protein atonal homolog 1, Class A basic helix-loop-helix protein 14, bHLHa14, Helix-loop-helix protein hATH-1, hATH1, ATOH1, ATH1, BHLHA14
Target/Specificity Math1
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsMath1 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATOH1
Synonyms ATH1, BHLHA14
Function Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity).
Cellular Location Nucleus. EMBL; U61148; AAB41305.1; -; Genomic_DNA EMBL; BC069145; AAH69145.1; -; mRNA EMBL; BC069594; AAH69594.1; -; mRNA EMBL; BC069604; AAH69604.1; -; mRNA EMBL; BC113623; AAI13624.1; -; mRNA EMBL; BC113625; AAI13626.1; -; mRNA CCDS; CCDS3638.1; - RefSeq; NP_005163.1; NM_005172.1 UniGene; Hs.532680; - ProteinModelPortal; Q92858; - SMR; Q92858; - BioGrid; 106964; 75 STRING; 9606.ENSP00000302216; - iPTMnet; Q92858; - PhosphoSitePlus; Q92858; - BioMuta; ATOH1; - DMDM; 3913115; - PaxDb; Q92858; - PeptideAtlas; Q92858; - PRIDE; Q92858; - ProteomicsDB; 75551; - DNASU; 474; - Ensembl; ENST00000306011; ENSP00000302216; ENSG00000172238 GeneID; 474; - KEGG; hsa:474; - UCSC; uc003hta.2; human CTD; 474; - DisGeNET; 474; - EuPathDB; HostDB:ENSG00000172238.4; - GeneCards; ATOH1; - HGNC; HGNC:797; ATOH1 MIM; 601461; gene neXtProt; NX_Q92858; - OpenTargets; ENSG00000172238; - PharmGKB; PA25095; - eggNOG; KOG4395; Eukaryota eggNOG; ENOG411269K; LUCA GeneTree; ENSGT00680000099860; - HOGENOM; HOG000261611; - HOVERGEN; HBG050609; - InParanoid; Q92858; - KO; K09083; - OMA; KQVNGVQ; - OrthoDB; EOG091G0R1N; - PhylomeDB; Q92858; - TreeFam; TF315153; - SIGNOR; Q92858; - GeneWiki; ATOH1; - GenomeRNAi; 474; - PRO; PR:Q92858; - Proteomes; UP000005640; Chromosome 4 Bgee; ENSG00000172238; - CleanEx; HS_ATOH1; - Genevisible; Q92858; HS GO; GO:0005634; C:nucleus; ISS:UniProtKB GO; GO:0031490; F:chromatin DNA binding; IEA:Ensembl GO; GO:0003700; F:DNA binding transcription factor activity; TAS:ProtInc GO; GO:0046983; F:protein dimerization activity; IEA:InterPro GO; GO:0000978; F:RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl GO; GO:0000981; F:RNA polymerase II transcription factor activity, sequence-specific DNA binding; ISA:NTNU_SB GO; GO:0001077; F:transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl GO; GO:0042668; P:auditory receptor cell fate determination; IEA:Ensembl GO; GO:0042667; P:auditory receptor cell fate specification; IEA:Ensembl GO; GO:0007411; P:axon guidance; IEA:Ensembl GO; GO:0007417; P:central nervous system development; TAS:ProtInc GO; GO:0021987; P:cerebral cortex development; IEA:Ensembl GO; GO:0042472; P:inner ear morphogenesis; IEA:Ensembl GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl GO; GO:0001764; P:neuron migration; IEA:Ensembl GO; GO:0007219; P:Notch signaling pathway; IEA:Ensembl GO; GO:0045609; P:positive regulation of inner ear auditory receptor cell differentiation; IEA:Ensembl GO; GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB GO; GO:0006366; P:transcription by RNA polymerase II; TAS:ProtInc CDD; cd00083; HLH; 1 Gene3D; 4.10.280.10; -; 1 InterPro; IPR032661; ATOH1 InterPro; IPR011598; bHLH_dom InterPro; IPR036638; HLH_DNA-bd_sf PANTHER; PTHR19290:SF82; PTHR19290:SF82; 1 Pfam; PF00010; HLH; 1 SMART; SM00353; HLH; 1 SUPFAM; SSF47459; SSF47459; 1 PROSITE; PS50888; BHLH; 1 2: Evidence at transcript level; Activator; Complete proteome; Developmental protein; Differentiation; DNA-binding; Neurogenesis; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation CHAIN 1 354 Protein atonal homolog 1 /FTId=PRO_0000127139 DOMAIN 159 211 bHLH. {ECO:0000255|PROSITE- ProRule:PRU00981} COMPBIAS 29 38 Poly-Pro COMPBIAS 224 228 Poly-Pro VARIANT 237 237 H -> Q (in dbSNP:rs35182771) /FTId=VAR_049539 SEQUENCE 354 AA; 38160 MW; AB12F1E917A00A8D CRC64; MSRLLHAEEW AEVKELGDHH RQPQPHHLPQ PPPPPQPPAT LQAREHPVYP PELSLLDSTD PRAWLAPTLQ GICTARAAQY LLHSPELGAS EAAAPRDEVD GRGELVRRSS GGASSSKSPG PVKVREQLCK LKGGVVVDEL GCSRQRAPSS KQVNGVQKQR RLAANARERR RMHGLNHAFD QLRNVIPSFN NDKKLSKYET LQMAQIYINA LSELLQTPSG GEQPPPPPAS CKSDHHHLRT AASYEGGAGN ATAAGAQQAS GGSQRPTPPG SCRTRFSAPA SAGGYSVQLD ALHFSTFEDS ALTAMMAQKN LSPSLPGSIL QPVQEENSKT SPRSHRSDGE FSPHSHYSDS DEAS
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to
info@abgent.com, and receive a free "I Love Antibodies" mug.
FeedBack
Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at tech@abgent.com.

$ 95.00
Cat# PBV10294b-50
Size:
Quantity:
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
“Crown Flash”  50 % off on 2,500+ Crown Antibodies. PromoCode:<span class=text-red> FLASH50
Terms & Conditions