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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Noxa Blocking Peptide   

Noxa Blocking Peptide

Product Information
Primary Accession Q13794
Other Accession AAH32663
Gene ID 5366
Calculated MW 6030 Da
Additional Information
Gene ID 5366
Application & Usage The peptide is used for blocking the antibody activity of active Noxa. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C
Other Names Phorbol-12-myristate-13-acetate-induced protein 1, PMA-induced protein 1, Immediate-early-response protein APR, Protein Noxa, PMAIP1, NOXA
Target/Specificity Noxa
Formulation 50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsNoxa Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms NOXA
Function Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
Cellular Location Mitochondrion
Tissue Location Highly expressed in adult T-cell leukemia cell line
Research Areas
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$ 95.00
Cat# PBV10299b
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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