|Calculated MW||39404 Da|
|Application & Usage||The peptide is used for blocking the antibody activity of active MAP-1. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C|
|Other Names||Modulator of apoptosis 1, MAP-1, Moap1|
|Formulation||50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.|
|Reconstitution & Storage||-20 °C|
|Precautions||MAP-1 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation (By similarity).|
|Tissue Location||Widely expressed, including in the brain. High expression levels in testis.|
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