BMP-14 (GDF-5/CDMP-1), human recombinant protein
Cartilage-derived morphogenetic protein-1, CDMP-1, LAP4, SYNS2, GDF-5, Radotermin, CDMP1, GDF5, Grow
|Calculated MW||27 kDa|
|Other Names||Cartilage-derived morphogenetic protein-1, CDMP-1, LAP4, SYNS2, GDF-5, Radotermin, CDMP1, GDF5, Growth differentiation factor 5, BMP-14|
|Application Notes||Reconstitute to a concentration of 0.1-1.0 mg/ml in H₂O containing BSA (50 mg BSA per 1 mg of protein). This solution can then be diluted into other aqueous buffers.|
|Storage||-20°C; Sterile filtered and lyophilized from 10 mM Sodium Citrate, pH 3.5.|
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BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. In addition to its osteogenic activity, BMP-14 is a principal inhibitor of cartilage development and is predominantly expressed in long bone during human embryonic development. Recombinant human BMP-14 is a 27 kDa homodimeric protein consisting of two 120 amino acid polypeptide chains.
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