Tom 40 Blocking Peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O96008 |
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Gene ID | 10452 |
Calculated MW | 37893 Da |
Gene ID | 10452 |
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Application & Usage | The peptide is used for blocking the antibody activity of Tom 40. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C |
Other Names | Mitochondrial import receptor subunit TOM40 homolog, Protein Haymaker, Translocase of outer membrane 40 kDa subunit homolog, p38.5, TOMM40, C19orf1, PEREC1, TOM40 |
Target/Specificity | Tom 40 |
Formulation | 50 µg (0.5mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | Tom 40 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TOMM40 |
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Synonyms | C19orf1, PEREC1, TOM40 |
Function | Channel-forming protein essential for import of protein precursors into mitochondria (PubMed:15644312, PubMed:31206022). Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by forming a complex with BCAP31 and mediating the translocation of Complex I components from the cytosol to the mitochondria (PubMed:31206022). |
Cellular Location | Mitochondrion outer membrane; Multi-pass membrane protein. Note=Associates with the mitochondria- associated ER membrane via interaction with BCAP31 |
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