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Gremlin 2, human recombinant protein

Gremlin 2

Product info
Primary Accession Q9H772
Calculated MW 17.2 kDa
Additional Info
Gene ID 64388
Gene Symbol GREM2
Other Names Gremlin-2, Cysteine knot superfamily 1, BMP antagonist 2, Protein related to DAN and cerberus, DAN domain family member 3
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 HPLC; ≥95%
Recombinant Yes
Application Notes Reconstitute to 1 mg/ml with sterilized dH₂O. Pipette to dissolve the protein pellet completely
Format Lyophilized protein
Storage -20°C; Sterile filtered and lyophilized with no additives
Citations (0)

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Gremlin (also known as Increased in High Glucose Protein 2, IHG-2, Down-regulated in Mos-transformed cells protein, Drm) functions as a bone morphogenetic protein (BMP) antagonist. It acts by binding to, and forming heterodimers with BMP-2, BMP-4, BMP-7, thus preventing them from interacting with their cell surface receptors. Recombinant human Gremlin-2 is a N-terminus His-tagged protein that was expressed from E. coli.


Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Katoh M.,et al.Oncol. Rep. 12:423-427(2004).

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$ 495.00
$ 3,950.00
$ 185.00
Cat# PBV10348r
(40 western blots)
Availability: 5-7days
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