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Elastase, Human Neutrophil recombinant protein

Leukocyte Elastase, ELA2

     
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Product info
Primary Accession P08246
Calculated MW 29.5 kDa
Additional Info
Gene ID 1991
Gene Symbol ELANE
Other Names Leukocyte Elastase, ELA2
Source Human Neutrophil
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 HPLC;
Recombinant No
Application Notes Deionized H₂O
Format Lyophilized protein
Storage -20°C; Salt- free lyophilized solid
Citations (0)

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Background

Elastase, like trypsin and chymotrypsin, is a serine protease that also hydrolyses amides and esters. It is produced in the pancreas as an inactive zymogen, proelastase, and activated in the duodenum by trypsin. Elastase is distinctive in that it acts upon elastin.This enzyme degrades elastin, collagen, and proteoglycan and has been implicated in the development of pulmonary emphesema and rheumatoid arthritis.

References

Nakamura H.,et al.Nucleic Acids Res. 15:9601-9601(1987).
Takahashi H.,et al.J. Biol. Chem. 263:14739-14747(1988).
Farley D.,et al.Biol. Chem. Hoppe-Seyler 370:737-744(1989).
Okano K.,et al.Biochem. Biophys. Res. Commun. 167:1326-1332(1990).
Okano K.,et al.J. Biochem. 102:13-16(1987).

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$ 335.00
Cat# PBV10371r-100
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