|Calculated MW||39518 Da|
|Application & Usage||The peptide is used for blocking the antibody activity of galectin-9. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.|
|Other Names||Galectin-9, Gal-9, Ecalectin, Tumor antigen HOM-HD-21, LGALS9|
|Formulation||50 µg (0.5 mg/ml) Galectin-9 peptide in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.|
|Reconstitution & Storage||-20 °C|
|Precautions||Galectin-9 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant.|
|Cellular Location||Cytoplasm. Secreted. Note=May also be secreted by a non-classical secretory pathway.|
|Tissue Location||Peripheral blood leukocytes and lymphatic tissues. Overexpressed in Hodgkin disease tissue|
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