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Myeloperoxidase (MPO) Blocking Peptide

     
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Product Information
Primary Accession P05164
Other Accession EAW94472.1
Gene ID 4353
Calculated MW 83869 Da
Additional Information
Gene ID 4353
Application & Usage The peptide is used for blocking the antibody activity of Myeloperoxidase. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Myeloperoxidase, MPO, 1.11.2.2, Myeloperoxidase, 89 kDa myeloperoxidase, 84 kDa myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain, MPO
Target/Specificity Myeloperoxidase (MPO)
Formulation 50 µg (0.5 mg/ml) Myeloperoxidase (MPO) peptide in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsMyeloperoxidase (MPO) Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MPO (HGNC:7218)
Function Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity (PubMed:9922160). Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage (PubMed:25698971).
Cellular Location Lysosome.
Research Areas
Citations (0)
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Discontinued
Cat# PBV10380b-50
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