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Human CellExp Progranulin, Human recombinant protein

Acrogranin, Paragranulin, Granulin-1

Product info
Primary Accession P28799
Concentration 0.5
Calculated MW 88.0 kDa
Additional Info
Gene ID 2896
Gene Symbol GRN
Other Names Acrogranin, Paragranulin, Granulin-1
Gene Source Human
Source HEK 293 cells
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 HPLC; ≥90%
Recombinant Yes
Format Liquid
Storage -20°C; Sterile filtered clear solution in PBS
Citations (0)

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Progranulin, also called proepithelin and PC cell-derived growth factor, is a single precursor protein of granulins which are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. Granulins are a variety of active, 6.0 kDa peptides and named granulin A (epithelin 1), granulin B (epithelin 2), granulin C, etc. Both the peptides and intact progranulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. Progranulin Human Recombinant fused to FLAG at C-terminus produced in HEK is a single, glycosylated, polypeptide chain containing 593 amino acids and having a molecular mass of 88.0 kDa. The Progranulin is purified by standard chromatographic techniques.


Bhandari V.,et al.Biochem. Biophys. Res. Commun. 188:57-63(1992).
Plowman G.D.,et al.J. Biol. Chem. 267:13073-13078(1992).
Bhandari V.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:1715-1719(1992).
Lu R.,et al.Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
Yu W.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.

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$ 225.00
$ 1,950.00
Cat# PBV10390r
(40 western blots)
Availability: 5-7days
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