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GDF-3, human recombinant protein

Growth/Differentiation Factor-3

     
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Product info
Primary Accession Q9NR23
Calculated MW 13 kDa
Additional Info
Gene ID 9573
Gene Symbol GDF3
Other Names Growth/Differentiation Factor-3
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC; ≥98%
Recombinant Yes
Application Notes Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers
Format Lyophilized protein
Storage -20°C; Sterile filtered and lyophilized with no additive
Citations (0)

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Background

GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type-2 diabetes. Recombinant human GDF-3 contains 114 amino acids polypeptide chains

References

Lorenz B.,et al.Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ye M.,et al.Hum. Mol. Genet. 19:287-298(2010).

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Cat# PBV10398r
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