|Calculated MW||22.255 kDa|
|Other Names||Growth hormone 1, Somatotropin, Pituitary growth hormone|
|Sequence||The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Thr-Phe-Pro-Ala|
|Application Notes||Centrifuge the vial prior to opening. Reconstitute in sterile H₂O or 0.4 % NaHCO₃ adjusted to pH 8-9 to a concentration ≥ 100 µg/ml and sterile filtered. This solution can then be diluted into other aqueous buffers, preferably in the presence of carrier protein.|
|Storage||-20°C; Lyophilized from 0.3 % NaHCO₃ , pH 8|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Growth Hormone Chicken Recombinant (cGH) produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 191 amino acids with an additional Ala at its N-terminus and having a molecular mass of 22255 Dalton. GH Chicken recombinant is purified by proprietary chromatographic techniques.
Lamb I.C.,et al.Nucleic Acids Res. 16:9339-9339(1988).
Zhvirblis G.S.,et al.Mol. Biol. (Mosk.) 21:1324-1328(1987).
Zhvirblis G.S.,et al.Mol. Biol. (Mosk.) 21:1620-1624(1987).
Baum D.,et al.Comp. Biochem. Physiol. 96B:491-495(1990).
Tanaka M.,et al.Gene 112:235-239(1992).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.