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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Dectin-1 Blocking Peptide   

Dectin-1 Blocking Peptide

Product Information
Primary Accession Q9BXN2
Other Accession EAW96155
Gene ID 64581
Calculated MW 27627 Da
Additional Information
Gene ID 64581
Application & Usage The peptide is used for blocking the antibody activity of Dectin-1. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names C-type lectin domain family 7 member A, Beta-glucan receptor, C-type lectin superfamily member 12, Dendritic cell-associated C-type lectin 1, DC-associated C-type lectin 1, Dectin-1, CLEC7A, BGR, CLECSF12, DECTIN1
Target/Specificity Dectin-1
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsDectin-1 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity).
Cellular Location Cell membrane; Single- pass type II membrane protein Isoform 6: Cytoplasm.
Tissue Location Highly expressed in peripheral blood leukocytes and dendritic cells. Detected in spleen, bone marrow, lung, muscle, stomach and placenta.
Research Areas
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$ 95.00
Cat# PBV10416b
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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