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Calretinin, murine recombinant protein
Calretinin, CR, Calb2, calbindin 2
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q08331 |
|---|---|
| Concentration | 0.1 |
| Calculated MW | 57 kDa |
| Gene ID | 12308 |
|---|---|
| Gene Symbol | Calb2 |
| Other Names | Calretinin, CR, Calb2, calbindin 2 |
| Gene Source | Mouse |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥90% |
| Assay2&Purity2 | HPLC; ≥90% |
| Recombinant | Yes |
| Format | Liquid |
| Storage | -20°C; Sterile filtered liquid (100 µg/ml) in 50 mM Tris-Acetate, pH 7.5, 1 mM EDTA, 20% Glycerol. |
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Background
Calretinin is an intraCellular calcium-binding protein belonging to the troponin C superfamily characterized by a structural motif described as the EF-hand domain. The immunohistochemical detection of calretinin in developing cerebellum is restricted to the later stages indicated by weak staining from week 21 of gestation, in Purkinje and basket cells and in neurons of the dentate nucleus. The intensity of staining increases as the cerebellum matures. In tumors, calretinin has been detected in mesotheliomas and some pulmonary adenocarcinomas. Recombinant Murine Calretinin protein is expressed from E. coli and purified by proprietary chromatographic techniques.
References
Tanaka Y.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Strauss K.I.,et al.Brain Res. Mol. Brain Res. 49:175-187(1997).
Lubec G.,et al.Submitted (JAN-2009) to UniProtKB.
Ellis J.,et al.Nucleic Acids Res. 21:5171-5178(1993).
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