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Isopeptidase T (short form), human recombinant protein

USP5; Ubiquitin-specific protease 5

     
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Product info
Primary Accession P45974
Concentration 2
Calculated MW 93.4 kDa
Additional Info
Gene ID 8078
Gene Symbol UBP5
Other Names USP5; Ubiquitin-specific protease 5
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 HPLC;
Recombinant Yes
Format Liquid
Storage -80°C; Supplied at a concentration of 2.0 mg/ml in 50 mM Tris, 10 mM β-mercaptoethanol, pH 7.5.
Citations (0)

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Background

Ubiquitin C-terminal hydrolases (UCHs) are a family of cysteine hydrolases that catalyze the UBPs hydrolyze isopeptide bonds between ubiquitin and the substrate protein or within polyubiquitin chains. Human isopeptidase T (isoT) is an UBP capable of binding ubiquitin that specifically disassembles free polyubiquitin chains linked through isopeptide bonds involving the K48 of ubiquitin into ubiquitin monomers.

References

Falquet L.,et al.FEBS Lett. 376:233-237(1995).
Ansari-Lari M.A.,et al.Genome Res. 6:314-326(1996).
Ansari-Lari M.A.,et al.Genome Res. 7:268-280(1997).
Tashayev V.L.,et al.Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 205.00
Cat# PBV10450r-25
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