|Calculated MW||54755 Da|
|Application & Usage||The peptide is used for blocking the antibody activity of GLUT4. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.|
|Other Names||Solute carrier family 2, facilitated glucose transporter member 4, GT2, Glucose transporter type 4, insulin-responsive, GLUT-4, Slc2a4, Glut-4, Glut4|
|Formulation||50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.|
|Reconstitution & Storage||-20 °C|
|Precautions||GLUT4 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Insulin-regulated facilitative glucose transporter.|
|Cellular Location||Cell membrane; Multi-pass membrane protein Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region Note=Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration (By similarity).|
|Tissue Location||Skeletal and cardiac muscles; brown and white fat|
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