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Human recombinant protein PRDX 4
Human Recombinant PRDX 4
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q13162 |
|---|---|
| Concentration | 1 |
| Calculated MW | 28.8 kDa |
| Gene ID | 10549 |
|---|---|
| Gene Symbol | PRDX4 |
| Other Names | Peroxiredoxin 4, PRX-4, AOE37-2, PRDX4. |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥90% |
| Assay2&Purity2 | N/A; |
| Recombinant | Yes |
| Sequence | MGSSHHHHHH SSGLVPRGSH MWETEERPRT REEECHFYAG GQVYPGEASR VSVADHSLHL SKAKISKPAP YWEGTAVIDG EFKELKLTDY RGKYLVFFFY PLDFTFVCPT EIIAFGDRLE EFRSINTEVV ACSVDSQFTH LAWINTPRRQ GGLGPIRIPL LSDLTHQISK DYGVYLEDSG HTLRGLFIID DKGILRQITL NDLPVGRSVD ETLRLVQAFQ YTDKHGEVCP AGWKPGSETI IPDPAGKLKY FDKLN |
| Format | Liquid |
| Storage | -80°C; 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Peroxiredoxin-4 in humans is encoded by the PRDX4 gene. The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. It is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappa B.
References
Jin D.-Y.,et al.J. Biol. Chem. 272:30952-30961(1997).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Xu G.,et al.Proc. Natl. Acad. Sci. U.S.A. 106:19310-19315(2009).
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Wagner E.,et al.Biochem. J. 366:777-785(2002).
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