|Calculated MW||38.8 kDa (354 aa, 1-334 aa + NT His-Tag)|
|Other Names||L-lactate dehydrogenase B chain, LDH-H, TRG-5.|
|Sequence||MGSSHHHHHH SSGLVPRGSH MATLKEKLIA PVAEEEATVP NNKITVVGVG QVGMACAISI LGKSLADELA LVDVLEDKLK GEMMDLQHGS LFLQTPKIVA DKDYSVTANS KIVVVTAGVR QQEGESRLNL VQRNVNVFKF IIPQIVKYSP DCIIIVVSNP VDILTYVTWK LSGLPKHRVI GSGCNLDSAR FRYLMAEKLG IHPSSCHGWI LGEHGDSSVA VWSGVNVAGV SLQELNPEMG TDNDSENWKE VHKMVVESAY EVIKLKGYTN WAIGLSVADL IESMLKNLSR IHPVSTMVKG MYGIENEVFL SLPCILNARG LTSVINQKLK DDEVAQLKKS ADTLWDIQKD LKDL|
|Storage||-80°C; 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT and 10% glycerol.|
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Provided below are standard protocols that you may find useful for product applications.
LDHB is part of the lactate dehydrogenase family. LDHB is an oxidoreductase which catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. LDHB catalyzes the oxidation of hydroxybutyrate, and frequently called Hydroxybutyrate Dehydrogenase (HBD). The LDH family consists of three members, LDH-A, LDH-B and LDH-C. LDHs function as powerful markers for germ cell tumors.
Takeno T.,et al.Biochem. J. 257:921-924(1989).
Sakai I.,et al.Biochem. J. 248:933-936(1987).
Bienvenut W.V.,et al.Submitted (MAY-2005) to UniProtKB.
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Scanlan M.J.,et al.Int. J. Cancer 83:456-464(1999).
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