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Human recombinant protein LDHB

Human Recombinant LDHB

     
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Product info
Primary Accession P07195
Concentration 1
Calculated MW 38.8 kDa (354 aa, 1-334 aa + NT His-Tag)
Additional Info
Gene ID 3945
Gene Symbol LDHB
Other Names L-lactate dehydrogenase B chain, LDH-H, TRG-5.
Gene Source Human
Source E. Coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Results >6 units/mg
Sequence MGSSHHHHHH SSGLVPRGSH MATLKEKLIA PVAEEEATVP NNKITVVGVG QVGMACAISI LGKSLADELA LVDVLEDKLK GEMMDLQHGS LFLQTPKIVA DKDYSVTANS KIVVVTAGVR QQEGESRLNL VQRNVNVFKF IIPQIVKYSP DCIIIVVSNP VDILTYVTWK LSGLPKHRVI GSGCNLDSAR FRYLMAEKLG IHPSSCHGWI LGEHGDSSVA VWSGVNVAGV SLQELNPEMG TDNDSENWKE VHKMVVESAY EVIKLKGYTN WAIGLSVADL IESMLKNLSR IHPVSTMVKG MYGIENEVFL SLPCILNARG LTSVINQKLK DDEVAQLKKS ADTLWDIQKD LKDL
Format Liquid
Storage -80°C; 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT and 10% glycerol.
Citations (0)

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Background

LDHB is part of the lactate dehydrogenase family. LDHB is an oxidoreductase which catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. LDHB catalyzes the oxidation of hydroxybutyrate, and frequently called Hydroxybutyrate Dehydrogenase (HBD). The LDH family consists of three members, LDH-A, LDH-B and LDH-C. LDHs function as powerful markers for germ cell tumors.

References

Takeno T.,et al.Biochem. J. 257:921-924(1989).
Sakai I.,et al.Biochem. J. 248:933-936(1987).
Bienvenut W.V.,et al.Submitted (MAY-2005) to UniProtKB.
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Scanlan M.J.,et al.Int. J. Cancer 83:456-464(1999).

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$ 275.00
Cat# PBV10611r-100
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