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Human recombinant protein TNF-beta/LTA

Human Recombinant TNF-beta/LTA

     
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product info
Primary Accession P01374
Concentration 0.5
Calculated MW 20.9 kDa (192 aa, 35-205 aa + His-Tag)
Additional Info
Gene ID 4049
Gene Symbol LTA
Other Names Lymphotoxin alpha, LT, TNFB, TNFSF1.
Gene Source Human
Source E. Coli
Assay&Purity SDS-PAGE; ≥90%
Assay2&Purity2 N/A;
Recombinant Yes
Results <0.3 ng/ml
Sequence MGSSHHHHHH SSGLVPRGSH MLPGVGLTPS AAQTARQHPK MHLAHSTLKP AAHLIGDPSK QNSLLWRANT DRAFLQDGFS LSNNSLLVPT SGIYFVYSQV VFSGKAYSPK ATSSPLYLAH EVQLFSSQYP FHVPLLSSQK MVYPGLQEPW LHSMYHGAAF QLTQGDQLST HTDGIPHLVL SPSTVFFGAF AL
Format Liquid
Storage -80°C; 0.5 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 30% glycerol.
Citations (0)

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Background

TNF-beta, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. It is highly inducible, secreted, and exists as homotrimeric molecule. It forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. It mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. It is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis.

References

Nedospasov S.A.,et al.Cold Spring Harb. Symp. Quant. Biol. 51:611-624(1986).
Nedwin G.E.,et al.J. Cell. Biochem. 29:171-181(1985).
Kobayashi Y.,et al.J. Biochem. 100:727-733(1986).
Gray P.W.,et al.Nature 312:721-724(1984).
Matsuyama N.,et al.FEBS Lett. 302:141-144(1992).

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$ 325.00
Cat# PBV10612r-50
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