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Human recombinant protein UBE2D2 (UbcH5b)

Human recombinant UBE2D2 (UbcH5b)

Product info
Primary Accession P62837
Calculated MW 17.729 kDa with His Tag.
Additional Info
Gene ID 7322
Gene Symbol UBE2D2
Other Names Human recombinant UBE2D2 (UbcH5b), ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5), UBC4, Ubiquitin carrier protein D2, Ubiquitin-conjugating enzyme E2-17 kDa 2, Ubiquitin-protein ligase D2, UBCH5B, EC, E2(17)KB2, PUBC1, UBC4/5, UBC5B, UBCH4.
Gene Source Human
Assay&Purity RP-HPLC; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Format Liquid
Storage -80°C; 75 µL of a 40 µM solution (3 nmoles) in 50 mM Tris, pH 7.5, 150 mM NaCl, 10 mM DTT and 10% glycerol.
Citations (0)

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UBE2D2 (UbcH5b) is an E2 (ubiquitin conjugating enzyme) that is involved in the conjugation of ubiquitin to target substrates along with E1 and E3 enzymes. The UbcH5 family (including UbcH5a and UbcH5c, 88% and 89% sequence identity with UbcH5b, respectively) are the human homologues of the Saccharomyces cerevisiae UBC4/5 family (~79% sequence identity). Members of the UbcH5 family have been implicated in a number of inflammatory and cancer pathways, including the ubiquitylation of p53 (involving the E3 ligase Hdm2) and IκBα (involving the E3 ligase SCF).


Jensen J.P.,et al.J. Biol. Chem. 270:30408-30414(1995).
Rolfe M.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:3264-3268(1995).
Guinn B.-A.,et al.Biochem. Biophys. Res. Commun. 335:1293-1304(2005).
Yin Y.,et al.Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 290.00
Cat# PBV10667r-3
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