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Human CellExp Beta-NGF, Human recombinant protein

Human Cellexp Human Recombinant Beta-NGF

     
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Product info
Primary Accession P01138
Calculated MW 13 kDa, non-disulfide bonded homodimer, non-glycosylated.
Additional Info
Gene ID 4803
Gene Symbol NGF
Other Names Beta Polypeptide, NGF, NGFB, HSAN5, Beta-NGF, MGC161426, MGC161428
Gene Source Human
Source Human cell expressed
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Results 1.5 to 8 ng/ml
Application Notes Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
Format Lyophilized
Storage -80°C; Lyophilized from a PBS solution.
Citations (0)

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Background

NGF-beta has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. The presence of beta NGF in immune cells and endocrine cells as well as in the CNS limbic areas suggests that beta NGF may function as an intracellular messenger to regulate the body’s response to stress. This product is produced in a human cell expression system with serum-free, chemically defined media.

References

Ullrich A.,et al.Nature 303:821-825(1983).
Ullrich A.,et al.Cold Spring Harb. Symp. Quant. Biol. 48:435-442(1983).
Borsani G.,et al.Nucleic Acids Res. 18:4020-4020(1990).
Tong Y.,et al.Zhongguo Ying Yong Sheng Li Xue Za Zhi 13:316-318(1997).
Kitano T.,et al.Mol. Biol. Evol. 21:936-944(2004).

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$ 215.00
$ 730.00
Cat# PBV10675r
Size:
Quantity:
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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