|Calculated MW||17 to 45 kDa, monomer, glycosylated|
|Other Names||MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor, IL-3, MGC79398, MGC79399.|
|Source||Human 293 cell expressed|
|Results||0.5 to 2 ng/ml|
|Application Notes||Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.|
|Storage||-80°C; Lyophilized from a PBS solution.|
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Provided below are standard protocols that you may find useful for product applications.
IL3 is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It stimulates colony formation of megakaryocytes, neutrophils, and macrophages from bone marrow cultures. It is also involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
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Schmutz J.,et al.Nature 431:268-274(2004).
Urdal D.L.,et al.Ann. N. Y. Acad. Sci. 554:167-176(1989).
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