|Calculated MW||17 to 45 kDa, monomer, glycosylated|
|Other Names||MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor, IL-3, MGC79398, MGC79399.|
|Source||Human 293 cell expressed|
|Results||0.5 to 2 ng/ml|
|Application Notes||Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.|
|Storage||-80°C; Lyophilized from a PBS solution.|
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Provided below are standard protocols that you may find useful for product applications.
IL3 is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It stimulates colony formation of megakaryocytes, neutrophils, and macrophages from bone marrow cultures. It is also involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
Dorssers L.,et al.Gene 55:115-124(1987).
Otsuka T.,et al.J. Immunol. 140:2288-2295(1988).
Yang Y.-C.,et al.Cell 47:3-10(1986).
Schmutz J.,et al.Nature 431:268-274(2004).
Urdal D.L.,et al.Ann. N. Y. Acad. Sci. 554:167-176(1989).
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