|Calculated MW||26 and 30 kDa, monomer, glycosylated|
|Other Names||IFN-b2, B cell differentiation factor, BCDF, BSF-2, HPGF, HSF, MGI-2, B-cell stimulatory factor 2, Interferon beta-2, Hybridoma growth factor, CTL differentiation factor, CDF, IL-6, HGF.|
|Source||Human 293 cell expressed|
|Assay&Purity||SDS-PAGE; > 95%|
|Results||0.2 to 1 ng/ml|
|Application Notes||Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.|
|Storage||-80°C; Lyophilized from a PBS solution.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Il-6 is a cytokine with a wide variety of biological functions. It is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. It plays an essential role in the final differentiation of b-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, it induces nerve cells differentiation and in hepatocytes it induces acute phase reactants.
Hirano T.,et al.Nature 324:73-76(1986).
Yasukawa K.,et al.EMBO J. 6:2939-2945(1987).
May L.T.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:8957-8961(1986).
Zilberstein A.,et al.EMBO J. 5:2529-2537(1986).
Brakenhoff J.P.J.,et al.J. Immunol. 139:4116-4121(1987).
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