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>   home   >   Products   >   Proteins   >   Human CellExp PDGF-AA, Human recombinant protein   

Human CellExp PDGF-AA, Human recombinant protein

Human Cellexp Human Recombinant PDGF-AA

Product info
Primary Accession P04085
Calculated MW 35, 40 and 45 kDa, homodimer, glycosylated
Additional Info
Gene ID 5154
Gene Symbol PDGFA
Other Names Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, PDGF-AA, PDGF-1.
Gene Source Human
Source Human 293 cell expressed
Assay&Purity SDS-PAGE; > 95%
Assay2&Purity2 N/A;
Recombinant Yes
Results 200 to 1000 ng/ml
Application Notes Reconstitute in sterile PBS containing 10 mM AcOH.
Format Lyophilized
Storage -80°C; Lyophilized from a solution of 10 mM AcOH.
Citations (0)

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PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGF is stored in platelet alpha-granules and released upon platelet activation. The PDGF is involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGF have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB.


Bonthron D.T.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:1492-1496(1988).
Rorsman F.,et al.Mol. Cell. Biol. 8:571-577(1988).
Betsholtz C.,et al.Nature 320:695-699(1986).
Hoppe J.,et al.FEBS Lett. 223:243-246(1987).
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).

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$ 270.00
$ 1,180.00
Cat# PBV10708r
(40 western blots)
Availability: 5-7days
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