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IFN-ω, human recombinant protein

IFN alpha II-1, IFNW1

     
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Product info
Primary Accession Q86WN2
Calculated MW 19.9 kDa
Additional Info
Gene ID 338376
Gene Symbol IFNE1
Other Names IFN alpha II-1, IFNW1
Gene Source Human
Source E Coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC;
Recombinant Yes
Sequence CDLPQNHGLL SRNTLVLLHQ MRRISPFLCL KDRRDFRFPQ EMVKGSQLQK AHVMSVLHEM LQQIFSLFHT ERSSAAWNMT LLDQLHTGLH QQLQHLETCL LQVVGEGESA GAISSPALTL RRYFQGIRVY LKEKKYSDCA WEVVRMEIMK SLFLSTNMQE RLRSKDRDLG SS
Target/Specificity IFN-ω
Application Notes Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Format Lyophilized powder
Storage -20°C; Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.
Citations (0)

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Background

IFN-ω is a type I interferon, which can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-α, IFN-β, and IFN-ω, signal through IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities. IFN-ω exhibits about 75% sequence homology with IFN-α, and contains two conserved disulfide bonds, which are necessary for full biological activity. Recombinant Human IFN-ω is a 19.9 kDa protein consisting of 172 amino acid residues.

References

Hardy M.P.,et al.Genomics 84:331-345(2004).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Fung K.Y.,et al.Science 339:1088-1092(2013).

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$ 75.00
$ 185.00
Cat# PBV10794r-10
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