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>   home   >   Products   >   Proteins   >   Human CellExp IL-22, human recombinant protein   

Human CellExp IL-22, human recombinant protein


Product info
Primary Accession Q9GZX6
Calculated MW Calculated MW of 17.2 kDa with no tag. The predicted N-terminus is Ala 34. DTT-reduced protein migrates as 18-33 kDa due to glycosylation.
Additional Info
Gene ID 50616
Gene Symbol IL-22
Other Names IL-22, IL-TIF, ZCYTO18
Gene Source Human
Source HEK 293 cells
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant Yes
Target/Specificity IL-22
Application Notes Centrifuge the vial prior to opening. Reconstitute in sterile deionized water to a concentration of 100 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Format Lyophilized powder
Storage -20°C; Lyophilized from 0.22 µm filtered solution in 20 mM Tris, 100 mM NaCl, pH 8.0. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
Citations (0)

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Interleukin-22 (IL22) is also known as cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor (IL-TIF), which is belongs to the IL-10 family or IL-10 superfamily (including IL-19, IL-20, IL-24, and IL-26), a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 biological activity is initiated by binding to a cell-surface complex composed of IL-22R1 and IL-10R2 receptor chains and further regulated by interactions with a soluble binding protein IL-22BP. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10.


Dumoutier L.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:10144-10149(2000).
Dumoutier L.,et al.Genes Immun. 1:488-494(2000).
Xie M.-H.,et al.J. Biol. Chem. 275:31335-31339(2000).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).

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$ 275.00
Cat# PBV10897r
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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