|Calculated MW||17.4 kDa|
|Other Names||Apolipoprotein A-II, Apo-AII, ApoA-II, APOA2.|
|Source||Human plasma. Prepared from plasma shown to be non-reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.|
|Assay&Purity||SDS-PAGE; ≥ 95% by SDS - PAGE|
|Storage||-80°C; Frozen in 10 mM NH4HCO3, pH 7.4|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
APOA2 stabilizes the HDL structure by its relationship with lipids, and plays a role in the HDL metabolism. APOA2 is the 2nd most abundant protein of the high density lipoprotein particles. 25% of Apo A in HDL is Apo AII. APOA2 is localized in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in APOA2 gene might cause apolipoprotein A-II deficiency or hypercholesterolemia. Levels of Apo AII in normal plasma range from 30-50 mg per 100 ml. The physiological role of the protein is unknown. Alcohol consumption, however, increases Apo AII levels.
Knott T.J.,et al.Biochem. Biophys. Res. Commun. 120:734-740(1984).
Moore M.N.,et al.Biochem. Biophys. Res. Commun. 123:1-7(1984).
Sharpe C.R.,et al.Nucleic Acids Res. 12:3917-3932(1984).
Lackner K.J.,et al.Nucleic Acids Res. 13:4597-4608(1985).
Knott T.J.,et al.Nucleic Acids Res. 13:6387-6398(1985).
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