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Lactalbumin, Human Milk recombinant protein


Product info
Primary Accession P00709
Calculated MW 14 kDa
Additional Info
Gene ID 3906
Gene Symbol LYZL7
Other Names LYZL7
Gene Source Human
Source Human Milk. Prepared from Human Milk shown to be non-reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA required tests.
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 N/A;
Recombinant No
Target/Specificity Lactalbumin
Application Notes Use deionized water
Format Lyophilized
Storage 4°C; Lyophilized from de-ionized water
Citations (0)

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α-Lactalbumin is an important whey protein in cow's milk, and is also present in the milk of many other mammalian species. In primates, alpha-lactalbumin expression is upregulated in response to the hormone prolactin and increases the production of lactose. α-Lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and β-1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transferring galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. When formed into a complex with Gal-T1, a galactosyltransferase, α-lactalbumin, enhances the enzyme's affinity for glucose by about 1000 times, and inhibits the ability to polymerize multiple galactose units. This gives rise to a pathway for forming lactose by converting Gal-TI to Lactose synthase.


Hall L.,et al.Nucleic Acids Res. 10:3503-3515(1982).
Hall L.,et al.Biochem. J. 242:735-742(1987).
Fujiwara Y.,et al.Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 225.00
$ 95.00
Cat# PBV10910r
(40 western blots)
Availability: 5-7days
Bulk Size
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