Trypsin, Human Pancreas recombinant protein
Beta-trypsin, Cationic trypsinogen, Serine protease 1, Trypsin I, PRSS1, TRP1, TRY1, TRYP1
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P07477 |
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Calculated MW | 21-23 kDa |
Gene ID | 5644 |
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Gene Symbol | TRYP1 |
Other Names | Beta-trypsin, Cationic trypsinogen, Serine protease 1, Trypsin I, PRSS1, TRP1, TRY1, TRYP1 |
Gene Source | Human |
Source | Human Pancreas |
Assay&Purity | SDS-PAGE; ≥95% |
Assay2&Purity2 | N/A; |
Recombinant | No |
Target/Specificity | Trypsin |
Application Notes | In water or aqueous buffer |
Format | Lyophilized |
Storage | -20°C; Lyophilized from 2 mM HCl. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Trypsin hydrolyzes peptides, amides, and ester bonds involving the carboxyl groups of L-arginine or L-lysine. Increased serum values of this enzyme and/or its zymogen (trypsinogen) have been found in patients with cystic fibrosis. Trypsinogen has three isoforms: cationic (trypsinogen 1), anionic (trypsinogen 2, MW - 22.5 kDa), and mesotrypsinogen (trypsinogen 3, MW - 25 kDa). The trypsin available from BioVision is the cationic form.
References
Emi M.,et al.Gene 41:305-310(1986).
Rowen L.,et al.Science 272:1755-1762(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Scherer S.W.,et al.Science 300:767-772(2003).
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